Is D57.21 a billable code?
No. D57.21 is a header code that groups 6 more specific codes. Use one of the billable codes listed on this page instead.
ICD-10-CM FY2027 diagnosis code
D57.21: Sickle-cell/Hb-C disease with crisis
Header code: not billableValid for dates of service October 1, 2026 to September 30, 2027
D57.21 groups related diagnoses under sickle-cell/hb-c disease with crisis. It cannot be used on a claim by itself. Choose the billable code below that matches the patient's record.
Billable codes under D57.21
- D57.211Sickle-cell/Hb-C disease with acute chest syndrome
- D57.212Sickle-cell/Hb-C disease with splenic sequestration
- D57.213Sickle-cell/Hb-C disease with cerebral vascular involvement
- D57.214Sickle-cell/Hb-C disease with dactylitis
- D57.218Sickle-cell/Hb-C disease with crisis with other specified complication
- D57.219Sickle-cell/Hb-C disease with crisis, unspecified
Other codes in D57.2 Sickle-cell/Hb-C disease
D57.21 questions
What does D57.21 mean?
D57.21 is the ICD-10-CM code for Sickle-cell/Hb-C disease with crisis. It is in chapter 3, Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89).
Code titles come from the official ICD-10-CM files published by the CDC National Center for Health Statistics. Always check payer rules and the clinical record before billing.