Is D89 a billable code?
No. D89 is a header code that groups 24 more specific codes. Use one of the billable codes listed on this page instead.
ICD-10-CM FY2027 diagnosis code
D89: Other disorders involving the immune mechanism, not elsewhere classified
Header code: not billableValid for dates of service October 1, 2026 to September 30, 2027
D89 groups related diagnoses under other disorders involving the immune mechanism, not elsewhere classified. It cannot be used on a claim by itself. Choose the billable code below that matches the patient's record.
Billable codes under D89
- D89.0Polyclonal hypergammaglobulinemia
- D89.1Cryoglobulinemia
- D89.2Hypergammaglobulinemia, unspecified
- D89.3Immune reconstitution syndrome
- D89.40Mast cell activation, unspecified
- D89.41Monoclonal mast cell activation syndrome
- D89.42Idiopathic mast cell activation syndrome
- D89.43Secondary mast cell activation
- D89.44Hereditary alpha tryptasemia
- D89.49Other mast cell activation disorder
- D89.810Acute graft-versus-host disease
- D89.811Chronic graft-versus-host disease
- D89.812Acute on chronic graft-versus-host disease
- D89.813Graft-versus-host disease, unspecified
- D89.82Autoimmune lymphoproliferative syndrome [ALPS]
- D89.831Cytokine release syndrome, grade 1
- D89.832Cytokine release syndrome, grade 2
- D89.833Cytokine release syndrome, grade 3
- D89.834Cytokine release syndrome, grade 4
- D89.835Cytokine release syndrome, grade 5
- D89.839Cytokine release syndrome, grade unspecified
- D89.84IgG4-related disease
- D89.89Other specified disorders involving the immune mechanism, not elsewhere classified
- D89.9Disorder involving the immune mechanism, unspecified
D89 questions
What does D89 mean?
D89 is the ICD-10-CM code for Other disorders involving the immune mechanism, not elsewhere classified. It is in chapter 3, Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89).
Code titles come from the official ICD-10-CM files published by the CDC National Center for Health Statistics. Always check payer rules and the clinical record before billing.