Is R65.21 a billable code?
Yes. R65.21 is a billable ICD-10-CM code and can be used on claims and superbills for dates of service from October 1, 2026 to September 30, 2027.
ICD-10-CM FY2027 diagnosis code
R65.21: Severe sepsis with septic shock
Billable codeValid for dates of service October 1, 2026 to September 30, 2027
R65.21 is a billable ICD-10-CM diagnosis code for severe sepsis with septic shock. It is specific enough to use on an insurance claim, a superbill or a Good Faith Estimate.
Superbill GeneratorStart a superbill with R65.21 already added.Good Faith EstimateStart a cost estimate with R65.21 already added.CMS-1500 Claim FormFill a claim form with R65.21 in box 21.
Other codes in R65.2 Severe sepsis
R65.21 questions
What does R65.21 mean?
R65.21 is the ICD-10-CM code for Severe sepsis with septic shock. It is in chapter 18, Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99).
Code titles come from the official ICD-10-CM files published by the CDC National Center for Health Statistics. Always check payer rules and the clinical record before billing.